nsmce1

ID

ZDB-GENE-040718-289

Name

NSE1 component of SMC5/6 complex

Symbol

nsmce1 Nomenclature History

Previous Names

zgc:92777

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein dimerization activity and ubiquitin protein ligase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA recombination. Predicted to be located in chromosome, telomeric region. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in head and post-vent region. Orthologous to human NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6900979 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nsmce1 Human Ortholog

No data available

Associated With nsmce1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR014857	Non-structural maintenance of chromosomes element 1, RING C4HC3-type
Family	IPR011513	Non-structural maintenance of chromosomes element 1
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily