Gene

psmb10

ID

ZDB-GENE-040718-278

Name

proteasome 20S subunit beta 10

Symbol

psmb10 Nomenclature History

Previous Names

beta2i
zgc:92791

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within proteolysis involved in protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 121 and proteosome-associated autoinflammatory syndrome 5. Orthologous to human PSMB10 (proteasome 20S subunit beta 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmb10 Human Ortholog

No data available

Associated With psmb10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR016050	Proteasome beta-type subunit, conserved site
Domain	IPR024689	Proteasome beta subunit, C-terminal
Family	IPR000243	Peptidase T1A, proteasome beta-subunit
Family	IPR001353	Proteasome, subunit alpha/beta
Family	IPR023333	Proteasome B-type subunit
Homologous_superfamily	IPR029055	Nucleophile aminohydrolases, N-terminal

Domain Details Per Protein

Protein	Additional Resources	Length	Nucleophile aminohydrolases, N-terminal	Peptidase T1A, proteasome beta-subunit	Proteasome beta subunit, C-terminal	Proteasome beta-type subunit, conserved site	Proteasome B-type subunit	Proteasome, subunit alpha/beta
UniProtKB:F1QR78	InterPro	276

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	psmb10-201 (1) Ensembl	Ensembl	1,125 nt	Select Tool ZFIN BLAST
mRNA	psmb10-202 (1) Ensembl	Ensembl	1,067 nt	Select Tool ZFIN BLAST
ncRNA	zgc:92791-003 (1) Ensembl	Ensembl	945 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations