Gene

ccdc103

ID
ZDB-GENE-040718-253
Name
coiled-coil domain containing 103
Symbol
ccdc103 Nomenclature History
Previous Names
  • smh (1)
  • zgc:100838 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Involved in axonemal dynein complex assembly; cerebrospinal fluid circulation; and embryonic heart tube morphogenesis. Localizes to axoneme. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; otic placode; peripheral olfactory organ; and spinal cord neural tube. Used to study primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 17. Orthologous to human CCDC103 (coiled-coil domain containing 103).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Panizzi et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccdc103 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 17 Alliance Ciliary dyskinesia, primary, 17 614679
Associated With ccdc103 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR025986 RNA-polymerase II-associated protein 3-like, C-terminal domain
Domain IPR031733 Dynein attachment factor, N-terminal
Family IPR042422 Coiled-coil domain-containing protein 103
Domain Details Per Protein
Protein Length Coiled-coil domain-containing protein 103 Dynein attachment factor, N-terminal RNA-polymerase II-associated protein 3-like, C-terminal domain
UniProtKB:Q6DGB6 247
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ccdc103 polyclonal Guinea pig
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations