Gene
impa1
- ID
- ZDB-GENE-040718-245
- Name
- inositol monophosphatase 1
- Symbol
- impa1 Nomenclature History
- Previous Names
-
- zgc:100926
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process and signal transduction. Predicted to act upstream of or within phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 59 and intellectual disability. Orthologous to human IMPA1 (inositol monophosphatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145589 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 59 | Alliance | Intellectual developmental disorder, autosomal recessive 59 | 617323 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR020583 | Inositol monophosphatase, metal-binding site |
| Conserved_site | IPR020550 | Inositol monophosphatase, conserved site |
| Family | IPR000760 | Inositol monophosphatase-like |
| Family | IPR020552 | Inositol monophosphatase, lithium-sensitive |
| Family | IPR033942 | Inositol monophosphatase |
Domain Details Per Protein
| Protein | Additional Resources | Length | Inositol monophosphatase | Inositol monophosphatase, conserved site | Inositol monophosphatase-like | Inositol monophosphatase, lithium-sensitive | Inositol monophosphatase, metal-binding site |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DGB2 | InterPro | 282 |
Interactions and Pathways
No data available
Plasmids
No data available