ZFIN ID: ZDB-GENE-040718-243
Gene Name: thymidine kinase 2
Gene Symbol: tk2
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:100948

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146682]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34152 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tk2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    mitochondrial DNA depletion syndrome 2 Mitochondrial DNA depletion syndrome 2 (myopathic type) 609560
    ?Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 3 617069
    DISEASE ASSOCIATED WITH tk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nucleobase-containing compound metabolic process (more)
    Cellular Component cellular_component (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002624 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR031314 (1)
  • Pfam:PF01712 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tk2-001 (1) 1377
    tk2-002 (1) 756
    tk2-003 (1) 870
    tk2-004 (1) 513
    ncRNA tk2-005 (1) 700
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tk2 No data available
    MARKER RELATIONSHIPS
    tk2Contained in: [BAC] CH211-189A15 (1) (order this)
    tk2Encodes: [EST] IMAGE:7146682 (1) (order this)
    [cDNA] MGC:100948 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002743 (1) 1400bp
    Genomic GenBank:CT027744 (1) 124535bp
    Select Tool
    Polypeptide UniProtKB:F8W4G9 (1) 268aa
    Sequence Clusters UniGene:78371 (1)
    Sequence Information (all 17)
    OTHER tk2 GENE PAGES
  • Alliance (1)
  • Gene:437016 (1)
  • VEGA:OTTDARG00000035401 (1)
  • ORTHOLOGY for tk2 (Chr: 7)
    CITATIONS (19)