Gene
sypb
- ID
- ZDB-GENE-040718-205
- Name
- synaptophysin b
- Symbol
- sypb Nomenclature History
- Previous Names
-
- zgc:136469
- zgc:92837
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have syntaxin-1 binding activity. Involved in glial cell development and retina development in camera-type eye. Predicted to localize to presynaptic active zone and synaptic vesicle membrane. Is expressed in central nervous system; lateral wall spinal cord; midbrain; retinal inner plexiform layer; and retinal outer plexiform layer. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human SYP (synaptophysin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 96 | Alliance | Intellectual developmental disorder, X-linked 96 | 300802 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Marvel domain | Synaptophysin/synaptoporin |
|---|---|---|---|
|
UniProtKB:B0S6H6
|
297 |
Interactions and Pathways
No data available
Plasmids