Gene

sypb

ID
ZDB-GENE-040718-205
Name
synaptophysin b
Symbol
sypb Nomenclature History
Previous Names
  • zgc:136469
  • zgc:92837
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have syntaxin-1 binding activity. Predicted to be involved in regulation of neuronal synaptic plasticity. Predicted to localize to presynaptic active zone and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Is expressed in central nervous system; lateral wall spinal cord; midbrain; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human SYP (synaptophysin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Charlton-Perkins et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sypb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability 96 Alliance Intellectual developmental disorder, X-linked 96 300802
Associated With sypb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008253 Marvel domain
Family IPR001285 Synaptophysin/synaptoporin
Family IPR028714 Synaptophysin
Domain Details Per Protein
Protein Length Marvel domain Synaptophysin Synaptophysin/synaptoporin
UniProtKB:Q4JQP7 297
UniProtKB:Q6DGP1 261
UniProtKB:B0S6H7 261
UniProtKB:B0S6H6 297
UniProtKB:A4FVL5 240
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations