Gene

meox1

ID
ZDB-GENE-040718-149
Name
mesenchyme homeobox 1
Symbol
meox1 Nomenclature History
Previous Names
  • mox2 (1)
  • mox (1)
  • cho
  • choker (1)
  • id:ibd2838
  • zgc:92343
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including hematopoietic stem cell differentiation; muscle cell development; and somite development. Localizes to nucleus. Is expressed in several structures, including fast muscle myoblast; medial rectus; paraxial mesoderm; pectoral fin; and tail bud. Used to study Klippel-Feil syndrome. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome 2. Orthologous to human MEOX1 (mesenchyme homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
23 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With meox1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Klippel-Feil syndrome 2 Alliance Klippel-Feil syndrome 2 214300
Associated With meox1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR042634 Homeobox protein MOX-1/MOX-2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily Homeobox protein MOX-1/MOX-2
UniProtKB:F1Q4R9 253
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-meox1
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations