Gene
pls3
- ID
- ZDB-GENE-040718-10
- Name
- plastin 3 (T isoform)
- Symbol
- pls3 Nomenclature History
- Previous Names
-
- wu:fc04g03
- zgc:91903
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in bone mineralization; embryonic cranial skeleton morphogenesis; and motor neuron axon guidance. Predicted to localize to actin filament; actin filament bundle; and cytoplasm. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human PLS3 (plastin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Conserved_site | IPR001589 | Actinin-type actin-binding domain, conserved site |
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR039959 | Fimbrin/Plastin |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Length | Actinin-type actin-binding domain, conserved site | Calponin homology domain | CH domain superfamily | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Fimbrin/Plastin |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DG81
|
627 |
Interactions and Pathways
No data available
Plasmids
No data available