ZFIN ID: ZDB-GENE-040628-1
Gene Name: RNA binding motif protein 24a
Gene Symbol: rbm24a    Nomenclature History

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Previous Names: rbm24, seb-4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Involved in several processes, including atrial cardiac muscle tissue development; embryonic organ morphogenesis; and positive regulation of sarcomere organization. Predicted to localize to cytosol; nucleus; and ribonucleoprotein complex. Is expressed in several structures, including cardiovascular system; cephalic musculature; segmental plate; sensory system; and solid lens vesicle. Used to study cataract and microphthalmia. Orthologous to human RBM24 (RNA binding motif protein 24).
Genome Resources: Alliance (1),  Gene:405801 (1),  Ensembl(GRCz11):ENSDARG00000102995 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sdu28 Small Deletion Exon 1 Unknown TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-rbm24a
1
MO1-rbm24a N/A 2
MO2-rbm24a N/A 1
MO3-rbm24a N/A 1
MO4-rbm24a N/A 1
MO5-rbm24a N/A 1
MO6-rbm24a N/A 1
TALEN1-rbm24a 1
DISEASE ASSOCIATED WITH rbm24a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rbm24a VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
cataract WT + MO6-rbm24a standard conditions Brastrom et al., 2019
microphthalmia WT + MO6-rbm24a standard conditions Brastrom et al., 2019
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiovascular system development (more)
Cellular Component cytoplasm (more)
Molecular Function mRNA 3'-UTR AU-rich region binding (more)
GO Terms (all 35)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rbm24a-201 (1)    Ensembl 664
rbm24a-202 (1)    Ensembl 3029
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rbm24a No data available
MARKER RELATIONSHIPS
rbm24a Contained in: [BAC] DKEY-108K24 (order this)
[Fosmid] CH1073-175O15 (1)
rbm24a Encodes: [cDNA] MGC:194503 (1), MGC:194514 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_212865 (1) 693 nt
Genomic GenBank:CU856207 (1) 55047 nt
Select Tool
Polypeptide UniProtKB:B3DI77 (1) 230 aa
Sequence Information (all 22)
ORTHOLOGY for rbm24a ( Chr: 19 )
CITATIONS (27)