Gene
lysmd3
- ID
- ZDB-GENE-040625-88
- Name
- LysM, putative peptidoglycan-binding, domain containing 3
- Symbol
- lysmd3 Nomenclature History
- Previous Names
-
- cb462 (1)
- sb:cb462
- wu:fb75a04
- zgc:86877
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in Golgi organization. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus. Is expressed in anterior axial hypoblast; axial mesoderm; axis; central nervous system; and notochord. Orthologous to human LYSMD3 (LysM domain containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb462 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa33702 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | LysM and putative peptidoglycan-binding domain-containing protein 1-4 | LysM domain | LysM domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q6IQA2 | InterPro | 305 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lysmd3-201
(1)
|
Ensembl | 1,700 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-147L19 | ZFIN Curated Data | |
| Encodes | EST | cb462 | Thisse et al., 2001 | |
| Encodes | EST | fb75a04 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:86877 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002104 (1) | 1611 nt | ||
| Genomic | GenBank:AL929202 (1) | 105855 nt | ||
| Polypeptide | UniProtKB:Q6IQA2 (1) | 305 aa |
- Casey, M.A., Hill, J.T., Hoshijima, K., Bryan, C.D., Gribble, S.L., Brown, J.T., Chien, C.B., Yost, H.J., Kwan, K.M. (2021) Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish. G3 (Bethesda). 12(3):
- Yokoyama, C.C., Baldridge, M.T., Leung, D.W., Zhao, G., Desai, C., Liu, T.C., Diaz-Ochoa, V.E., Huynh, J.P., Kimmey, J.M., Sennott, E.L., Hole, C.R., Idol, R.A., Park, S., Storek, K.M., Wang, C., Hwang, S., Milam, A.V., Chen, E., Kerrinnes, T., Starnbach, M.N., Handley, S.A., Mysorekar, I.U., Allen, P.M., Monack, D.M., Dinauer, M.C., Doering, T.L., Tsolis, R.M., Dworkin, J.E., Stallings, C.L., Amarasinghe, G.K., Micchelli, C.A., Virgin, H.W. (2018) LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.. The Journal of biological chemistry. 293(16):6022-6038
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Uusi-Heikkilä, S., Whiteley, A.R., Kuparinen, A., Matsumura, S., Venturelli, P.A., Wolter, C., Slate, J., Primmer, C.R., Meinelt, T., Killen, S.S., Bierbach, D., Polverino, G., Ludwig, A., Arlinghaus, R. (2015) The evolutionary legacy of size-selective harvesting extends from genes to populations. Evolutionary Applications. 8:597-620
- Laroche, F.J., Tulotta, C., Lamers, G.E., Meijer, A.H., Yang, P., Verbeek, F.J., Blaise, M., Stougaard, J., and Spaink, H.P. (2013) The embryonic expression patterns of zebrafish genes encoding LysM-domains. Gene expression patterns : GEP. 13(7):212-24
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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