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ZIRC
ZFIN ID: ZDB-GENE-040625-77
Gene Name: BRICK1 subunit of SCAR/WAVE actin nucleating complex
Gene Symbol: brk1
Sequence Ontology ID : SO:0001217

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Previous Name: zgc:86903

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to be involved in cell motility and regulation of actin polymerization or depolymerization. Predicted to localize to the SCAR complex. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6905320]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027276Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH brk1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH brk1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament organization (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein-containing complex binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR033378 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA brk1-201 (1) 878
    brk1-202 (1) 1414
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM brk1 No data available
    MARKER RELATIONSHIPS
    brk1 Contained in: [BAC] DKEY-51M8 (1) (order this), DKEYP-87F2 (1)
    brk1 Encodes: [EST] IMAGE:6905320 (1) (order this)
    [cDNA] MGC:86903 (1) (order this), MGC:172205 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002097 (1) 1023 bp
    Genomic GenBank:CT737233 (1) 132161 bp
    Select Tool
    Polypeptide UniProtKB:G1K2N2 (1) 83 aa
    Sequence Clusters UniGene:162070 (1)
    Sequence Information (all 21)
    ORTHOLOGY for brk1 ( Chr: 11 )
    CITATIONS (23)