Gene
cbx1b
- ID
- ZDB-GENE-040625-68
- Name
- chromobox homolog 1b (HP1 beta homolog Drosophila)
- Symbol
- cbx1b Nomenclature History
- Previous Names
-
- zgc:86924
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in heterochromatin formation. Predicted to be located in nucleus. Predicted to be active in pericentric heterochromatin. Orthologous to human CBX1 (chromobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023779 | Chromo domain, conserved site |
| Domain | IPR000953 | Chromo/chromo shadow domain |
| Domain | IPR008251 | Chromo shadow domain |
| Domain | IPR017984 | Chromo domain subgroup |
| Domain | IPR023780 | Chromo domain |
| Family | IPR051219 | Heterochromatin-associated chromo domain-containing protein |
| Homologous_superfamily | IPR016197 | Chromo-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Chromo/chromo shadow domain | Chromo domain | Chromo domain, conserved site | Chromo domain subgroup | Chromo-like domain superfamily | Chromo shadow domain | Heterochromatin-associated chromo domain-containing protein |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B2K9 | InterPro | 202 | |||||||
| UniProtKB:U3JB43 | InterPro | 127 | |||||||
| UniProtKB:Q6IQ71 | InterPro | 203 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cbx1b-201
(1)
|
Ensembl | 1,656 nt | ||
| mRNA |
cbx1b-202
(1)
|
Ensembl | 1,704 nt | ||
| mRNA |
cbx1b-203
(1)
|
Ensembl | 1,050 nt | ||
| mRNA |
cbx1b-204
(1)
|
Ensembl | 866 nt | ||
| mRNA |
cbx1b-205
(1)
|
Ensembl | 546 nt | ||
| mRNA |
cbx1b-206
(1)
|
Ensembl | 784 nt | ||
| ncRNA |
cbx1b-004
(1)
|
Ensembl | 529 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-81K8 | ZFIN Curated Data | |
| Contained in | BAC | CH211-194K22 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:86924 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002090 (1) | 1694 nt | ||
| Genomic | GenBank:BX248092 (1) | 217001 nt | ||
| Polypeptide | UniProtKB:Q6IQ71 (1) | 203 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Rakshambikai, R., Srinivasan, N., and Gadkari, R.A. (2014) Repertoire of protein kinases encoded in the genome of zebrafish shows remarkably large population of PIM kinases. Journal of Bioinformatics and Computational Biology. 12(1):1350014
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 6 of 6
Show