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Gene

sae1

ID
ZDB-GENE-040625-21
Name
SUMO1 activating enzyme subunit 1
Symbol
sae1 Nomenclature History
Previous Names
  • fa28b04
  • sae2a (1)
  • uble1a (1)
  • wu:fa28b04 (1)
  • zgc:86633
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable SUMO activating enzyme activity and protein C-terminus binding activity. Acts upstream of or within definitive hemopoiesis; hematopoietic stem cell homeostasis; and protein sumoylation. Predicted to be located in nucleus. Predicted to be part of SUMO activating enzyme complex. Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human SAE1 (SUMO1 activating enzyme subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sae1 Human Ortholog
No data available
Associated With sae1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000594 THIF-type NAD/FAD binding fold
Family IPR000011 Ubiquitin/SUMO-activating enzyme E1
Homologous_superfamily IPR035985 Ubiquitin-activating enzyme
Domain Details Per Protein
Protein Length THIF-type NAD/FAD binding fold Ubiquitin-activating enzyme Ubiquitin/SUMO-activating enzyme E1
UniProtKB:Q6IQS6 348
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations