Gene
ndufa1
- ID
- ZDB-GENE-040625-168
- Name
- NADH:ubiquinone oxidoreductase subunit A1
- Symbol
- ndufa1 Nomenclature History
- Previous Names
-
- zgc:86674
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 12. Orthologous to human NDUFA1 (NADH:ubiquinone oxidoreductase subunit A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Burkhalter et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 12 | Alliance | Mitochondrial complex I deficiency, nuclear type 12 | 301020 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR017384 | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 |
|---|---|---|
|
UniProtKB:F1QQ42
|
71 | |
|
UniProtKB:Q6IQP6
|
59 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa1-201
(1)
|
Ensembl | 366 nt | ||
| mRNA |
ndufa1-202
(1)
|
Ensembl | 1,203 nt | ||
| mRNA |
ndufa1-203
(1)
|
Ensembl | 318 nt |
Interactions and Pathways
No data available
Plasmids
No data available