Gene
med22
- ID
- ZDB-GENE-040625-156
- Name
- mediator complex subunit 22
- Symbol
- med22 Nomenclature History
- Previous Names
-
- surf5 (1)
- wu:fj45h07
- zgc:86721
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED22 (mediator complex subunit 22).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009332 | Mediator of RNA polymerase II transcription subunit 22 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Mediator of RNA polymerase II transcription subunit 22 |
|---|---|---|---|
| UniProtKB:A0A8M9PXA1 | InterPro | 140 | |
| UniProtKB:A0A8M2BJ43 | InterPro | 198 | |
| UniProtKB:A5WUL3 | InterPro | 198 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-278C20 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-125I20 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-226M8 | ZFIN Curated Data | |
| Encodes | EST | fj45h07 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:86721 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002144 (1) | 1311 nt | ||
| Genomic | GenBank:BX927184 (1) | 160345 nt | ||
| Polypeptide | UniProtKB:A0A8M2BJ43 (1) | 198 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Shkumatava, A., Stark, A., Sive, H., and Bartel, D.P. (2009) Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Genes & Development. 23(4):466-481
- Turcot-Dubois, A.L., Le Moullac-Vaidye, B., Despiau, S., Roubinet, F., Bovin, N., Le Pendu, J., and Blancher, A. (2007) Long Term Evolution of the Cazy Glycosyltransferase 6 (ABO) Gene Family from Fishes to Mammals: A Birth-and-Death Evolution Model. Glycobiology. 17(5):516-528
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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