Gene
tmx2b
- ID
- ZDB-GENE-040625-105
- Name
- thioredoxin-related transmembrane protein 2b
- Symbol
- tmx2b Nomenclature History
- Previous Names
-
- tmx2
- fb73h06
- txndc14
- wu:fb73h06 (1)
- zgc:86830
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable disulfide oxidoreductase activity. Predicted to be involved in brain development. Predicted to be located in endoplasmic reticulum and mitochondrial membrane. Predicted to be active in endoplasmic reticulum membrane; mitochondria-associated endoplasmic reticulum membrane contact site; and mitochondrion. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with microcephaly, cortical malformations, and spasticity | 618730 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Thioredoxin domain | Thioredoxin-like superfamily | Thioredoxin-related transmembrane protein 2 | Thioredoxin-related transmembrane protein 2, thioredoxin domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6IQC7
|
307 |
Interactions and Pathways
No data available
Plasmids
No data available