Gene

dact1

ID
ZDB-GENE-040623-3
Name
dishevelled-binding antagonist of beta-catenin 1
Symbol
dact1 Nomenclature History
Previous Names
  • dapper1 (1)
  • dpr1 (1)
  • frd1 (1)
  • frodo1 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Acts upstream of or within Wnt signaling pathway. Predicted to be active in cytoplasm. Is expressed in several structures, including germ ring; immature eye; mesoderm; nervous system; and neural plate. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome. Orthologous to human DACT1 (dishevelled binding antagonist of beta catenin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Waxman et al., 2004
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dact1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Townes-Brocks syndrome 2 617466
Associated With dact1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR024843 Dapper
Family IPR024848 Dact1
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations