Gene
rps29
- ID
- ZDB-GENE-040622-5
- Name
- ribosomal protein S29
- Symbol
- rps29 Nomenclature History
- Previous Names
-
- zgc:113935
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within several processes, including blood vessel morphogenesis; hemopoiesis; and intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 13. Orthologous to human RPS29 (ribosomal protein S29).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6905321 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| hi2903Tg | Transgenic insertion | Intron 1 | Unknown | DNA |
1 - 1 of 1
Show
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 13 | Alliance | Diamond-Blackfan anemia 13 | 615909 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018271 | Small ribosomal subunit protein uS14, conserved site |
| Family | IPR001209 | Small ribosomal subunit protein uS14 |
| Family | IPR039744 | Small ribosomal subunit protein uS14, eukaryotes/archaea |
| Homologous_superfamily | IPR043140 | Small ribosomal subunit protein uS14 superfamily |
1 - 4 of 4
Domain Details Per Protein
| Protein | Additional Resources | Length | Small ribosomal subunit protein uS14 | Small ribosomal subunit protein uS14, conserved site | Small ribosomal subunit protein uS14, eukaryotes/archaea | Small ribosomal subunit protein uS14 superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6Q419 | InterPro PDB | 56 |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-301C19 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:6905321 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:113935 | ZFIN Curated Data | |
| Has Artifact | cDNA | MGC:103593 |
1 - 4 of 4
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_212953 (1) | 302 nt | ||
| Genomic | GenBank:CU633785 (2) | 83437 nt | ||
| Polypeptide | UniProtKB:Q6Q419 (1) | 56 aa |
- Thomas, R.C., Zaksauskaite, R., Al-Kandari, N.Y., Hyde, A.C., Abugable, A.A., El-Khamisy, S.F., van Eeden, F.J. (2024) Second generation lethality in RNAseH2a knockout zebrafish. Nucleic acids research. 52(18):11014-11028
- Bastos de Oliveira, M., Meier, K., Jung, S., Bartels-Klein, E., Coxam, B., Geudens, I., Szymborska, A., Skoczylas, R., Fechner, I., Koltowska, K., Gerhardt, H. (2021) Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk. Development (Cambridge, England). 148(4):
- Zaksauskaite, R., Thomas, R.C., van Eeden, F., El-Khamisy, S.F. (2021) Tdp1 protects from topoisomerase 1-mediated chromosomal breaks in adult zebrafish but is dispensable during larval development. Science advances. 7(5):
- Takemoto, K., Imai, Y., Saito, K., Kawasaki, T., Carlton, P.M., Ishiguro, K.I., Sakai, N. (2020) Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes. PLoS Genetics. 16:e1008640
- Taylor, A.M., Macari, E.R., Chan, I.T., Blair, M.C., Doulatov, S., Vo, L.T., Raiser, D.M., Siva, K., Basak, A., Pirouz, M., Shah, A.N., McGrath, K., Humphries, J.M., Stillman, E., Alter, B.P., Calo, E., Gregory, R.I., Sankaran, V.G., Flygare, J., Ebert, B.L., Zhou, Y., Daley, G.Q., Zon, L.I. (2020) Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12(566):
- Baek, S., Oh, T.G., Secker, G., Sutton, D.L., Okuda, K.S., Paterson, S., Bower, N.I., Toubia, J., Koltowska, K., Capon, S.J., Baillie, G.J., Simons, C., Muscat, G.E.O., Lagendijk, A.K., Smith, K.A., Harvey, N.L., Hogan, B.M. (2019) The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage. Developmental Cell. 49:279-292.e5
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Bower, N.I., Vogrin, A.J., Le Guen, L., Chen, H., Stacker, S.A., Achen, M.G., Hogan, B.M. (2017) Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development. Development (Cambridge, England). 144(3):507-518
- Chen, J., Tanguay, R.L., Xiao, Y., Haggard, D.E., Ge, X., Jia, Y., Zheng, Y., Dong, Q., Huang, C., Lin, K. (2016) TBBPA exposure during a sensitive developmental window produces neurobehavioral changes in larval zebrafish. Environmental pollution (Barking, Essex : 1987). 216:53-63
- Fongang, B., Kudlicki, A. (2016) Comparison between Timelines of Transcriptional Regulation in Mammals, Birds, and Teleost Fish Somitogenesis. PLoS One. 11:e0155802
1 - 10 of 28
Show