ZFIN is now using GRCz12tu for Genomic Data
Gene
rnaseh2a
- ID
- ZDB-GENE-040426-976
- Name
- ribonuclease H2, subunit A
- Symbol
- rnaseh2a Nomenclature History
- Previous Names
-
- zgc:56307
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in ribonucleotide excision repair. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2A (ribonuclease H2 subunit A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144748 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Aicardi-Goutieres syndrome | Alliance | Aicardi-Goutieres syndrome 4 | 610333 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR024567 | Ribonuclease HII/HIII domain |
| Family | IPR001352 | Ribonuclease HII/HIII |
| Family | IPR004649 | Ribonuclease H2, subunit A |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR023160 | Ribonuclease HII, helix-loop-helix cap domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ribonuclease H2, subunit A | Ribonuclease HII, helix-loop-helix cap domain superfamily | Ribonuclease HII/HIII | Ribonuclease HII/HIII domain | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6IQM9 | InterPro | 307 | ||||||
| UniProtKB:A0AC58H6S5 | InterPro | 207 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rnaseh2a-202
(1)
|
Ensembl | 787 nt | ||
| mRNA |
rnaseh2a-201
(1)
|
Ensembl | 1,302 nt | ||
| mRNA |
rnaseh2a-203
(1)
|
Ensembl | 1,089 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers