Gene

cox15

ID
ZDB-GENE-040426-955
Name
cytochrome c oxidase assembly homolog 15 (yeast)
Symbol
cox15 Nomenclature History
Previous Names
  • wu:fa18g06
  • zgc:56240
  • zgc:77422
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme a biosynthetic process. Predicted to localize to mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox15 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial complex IV deficiency nuclear type 6 Alliance Mitochondrial complex IV deficiency, nuclear type 6 615119
Associated With cox15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR003780 COX15/CtaA family
Family IPR023754 Heme A synthase, type 2
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Domain Details Per Protein
Protein Length COX15/CtaA family Heme A synthase, type 2 Peptidase S1, PA clan
UniProtKB:F1R355 399
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations