Gene
ubap1
- ID
- ZDB-GENE-040426-950
- Name
- ubiquitin associated protein 1
- Symbol
- ubap1 Nomenclature History
- Previous Names
-
- zgc:56228
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to localize to ESCRT I complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Orthologous to human UBAP1 (ubiquitin associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56228 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 80 | Alliance | Spastic paraplegia 80, autosomal dominant | 618418 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR015940 | Ubiquitin-associated domain |
| Domain | IPR023340 | UMA domain |
| Domain | IPR049467 | Ubiquitin-associated protein 1-like, UBA2 domain |
| Family | IPR038870 | Ubiquitin-associated protein 1 |
| Homologous_superfamily | IPR009060 | UBA-like superfamily |
| Homologous_superfamily | IPR042575 | Ubiquitin-associated protein 1, C-terminal |
Domain Details Per Protein
| Protein | Length | UBA-like superfamily | Ubiquitin-associated domain | Ubiquitin-associated protein 1 | Ubiquitin-associated protein 1, C-terminal | Ubiquitin-associated protein 1-like, UBA2 domain | UMA domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6P6X0
|
453 |
Interactions and Pathways
No data available
Plasmids
No data available