Gene

ubap1

ID
ZDB-GENE-040426-950
Name
ubiquitin associated protein 1
Symbol
ubap1 Nomenclature History
Previous Names
  • zgc:56228
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to localize to ESCRT I complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Orthologous to human UBAP1 (ubiquitin associated protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ubap1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Spastic paraplegia 80, autosomal dominant 618418
Associated With ubap1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR015940 Ubiquitin-associated domain
Domain IPR023340 UMA domain
Family IPR038870 Ubiquitin-associated protein 1
Homologous_superfamily IPR009060 UBA-like superfamily
Homologous_superfamily IPR042575 Ubiquitin-associated protein 1, C-terminal
Domain Details Per Protein
Protein Length UBA-like superfamily Ubiquitin-associated domain Ubiquitin-associated protein 1 Ubiquitin-associated protein 1, C-terminal UMA domain
UniProtKB:F6P6X0 453
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations