Gene
fxr2
- ID
- ZDB-GENE-040426-943
- Name
- FMR1 autosomal homolog 2
- Symbol
- fxr2 Nomenclature History
- Previous Names
-
- id:ibd5046
- zgc:56215
- zgc:77472
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have mRNA 3'-UTR binding activity; protein homodimerization activity; and translation regulator activity. Predicted to be involved in several processes, including positive regulation of response to DNA damage stimulus; regulation of filopodium assembly; and regulation of gene expression. Predicted to localize to several cellular components, including dendrite; polysome; and postsynaptic density. Is expressed in mesoderm; musculature system; and somite. Orthologous to human FXR2 (FMR1 autosomal homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56215 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004087 | K Homology domain |
| Domain | IPR004088 | K Homology domain, type 1 |
| Domain | IPR008395 | Agenet-like domain |
| Domain | IPR022034 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core |
| Domain | IPR032172 | Fragile X-related protein 1, C-terminal region 1 |
| Domain | IPR040472 | Synaptic functional regulator FMRP, KH0 domain |
| Domain | IPR041560 | FMR1, tudor domain |
| Domain | IPR047420 | RNA-binding protein FXR2, second Tudor-like Agenet domain |
| Domain | IPR047421 | RNA-binding protein FXR2, first Tudor-like Agenet domain |
| Domain | IPR047422 | RNA-binding protein FXR2, first type I K homology domain |
| Domain | IPR047424 | RNA-binding protein FXR2, second type I K homology domain |
| Family | IPR040148 | Fragile X messenger ribonucleoprotein 1 |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Length | Agenet-like domain | FMR1, tudor domain | Fragile X messenger ribonucleoprotein 1 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core | Fragile X-related protein 1, C-terminal region 1 | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | RNA-binding protein FXR2, first Tudor-like Agenet domain | RNA-binding protein FXR2, first type I K homology domain | RNA-binding protein FXR2, second Tudor-like Agenet domain | RNA-binding protein FXR2, second type I K homology domain | Synaptic functional regulator FMRP, KH0 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NY99
|
676 |
Interactions and Pathways
No data available
Plasmids
No data available