Gene
pex12
- ID
- ZDB-GENE-040426-929
- Name
- peroxisomal biogenesis factor 12
- Symbol
- pex12 Nomenclature History
- Previous Names
-
- zgc:56182
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein import into peroxisome matrix and protein monoubiquitination. Predicted to act upstream of or within protein targeting to peroxisome. Predicted to be located in membrane and peroxisome. Predicted to be part of peroxisomal importomer complex. Predicted to be active in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Orthologous to human PEX12 (peroxisomal biogenesis factor 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| peroxisome biogenesis disorder 3A | Alliance | Peroxisome biogenesis disorder 3A (Zellweger) | 614859 |
| peroxisome biogenesis disorder 3B | Alliance | Peroxisome biogenesis disorder 3B | 266510 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Peroxisome assembly protein 12 | Pex, N-terminal | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|
|
UniProtKB:B0R157
|
350 |
Interactions and Pathways
No data available
Plasmids
No data available