Gene
aacs
- ID
- ZDB-GENE-040426-903
- Name
- acetoacetyl-CoA synthetase
- Symbol
- aacs Nomenclature History
- Previous Names
-
- zgc:56105 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and acetoacetate-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Predicted to localize to cytosol. Is expressed in liver; nervous system; neural tube; and optic vesicle. Orthologous to human AACS (acetoacetyl-CoA synthetase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136547 (6 images)
- IMAGE:7149117 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020845 | AMP-binding, conserved site |
| Domain | IPR000873 | AMP-dependent synthetase/ligase domain |
| Domain | IPR032387 | Acetyl-coenzyme A synthetase, N-terminal domain |
| Family | IPR005914 | Acetoacetyl-CoA synthase |
| Homologous_superfamily | IPR042099 | ANL, N-terminal domain |
| Homologous_superfamily | IPR045851 | AMP-binding enzyme, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Acetoacetyl-CoA synthase | Acetyl-coenzyme A synthetase, N-terminal domain | AMP-binding, conserved site | AMP-binding enzyme, C-terminal domain superfamily | AMP-dependent synthetase/ligase domain | ANL, N-terminal domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A3QK15
|
673 |
Interactions and Pathways
No data available
Plasmids
No data available