Gene

pdgfrl

ID

ZDB-GENE-040426-901

Name

platelet-derived growth factor receptor-like

Symbol

pdgfrl Nomenclature History

Previous Names

zgc:56104
zgc:77677

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Exhibits identical protein binding activity. Human ortholog(s) of this gene implicated in colorectal cancer and hepatocellular carcinoma. Is expressed in cranium; head mesenchyme; notochord; sclerotome; and somite. Orthologous to human PDGFRL (platelet derived growth factor receptor like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56104 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pdgfrl Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
colorectal cancer	Alliance	Colorectal cancer, somatic	114500
hepatocellular carcinoma	Alliance	Hepatocellular cancer, somatic	114550

Associated With pdgfrl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Family	IPR042495	Platelet-derived growth factor receptor-like protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily