Gene
washc5
- ID
- ZDB-GENE-040426-838
- Name
- WASH complex subunit 5
- Symbol
- washc5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Acts upstream of or within several processes, including axonogenesis; heart contraction; and regulation of cardiac myofibril assembly. Predicted to be located in early endosome. Predicted to be part of WASH complex. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 1 and hereditary spastic paraplegia 8. Orthologous to human WASHC5 (WASH complex subunit 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bu et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 8 | Alliance | Spastic paraplegia 8, autosomal dominant | 603563 |
| Ritscher-Schinzel syndrome 1 | Alliance | Ritscher-Schinzel syndrome 1 | 220210 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019393 | WASH complex, subunit strumpellin |
Domain Details Per Protein
| Protein | Length | WASH complex, subunit strumpellin |
|---|---|---|
|
UniProtKB:Q7ZVM1
|
1159 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
washc5-201
(1)
|
Ensembl | 3,228 nt |
Interactions and Pathways
No data available
Plasmids
No data available