Gene

apex2

ID
ZDB-GENE-040426-835
Name
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Symbol
apex2 Nomenclature History
Previous Names
  • zgc:55889 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Predicted to be involved in base-excision repair. Predicted to localize to nucleus. Orthologous to human APEX2 (apurinic/apyrimidinic endodeoxyribonuclease 2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apex2 Human Ortholog
No data available
Associated With apex2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR020847 AP endonuclease 1, binding site
Domain IPR005135 Endonuclease/exonuclease/phosphatase
Domain IPR010666 Zinc finger, GRF-type
Family IPR004808 AP endonuclease 1
Homologous_superfamily IPR036691 Endonuclease/exonuclease/phosphatase superfamily
Domain Details Per Protein
Protein Length AP endonuclease 1 AP endonuclease 1, binding site Endonuclease/exonuclease/phosphatase Endonuclease/exonuclease/phosphatase superfamily Zinc finger, GRF-type
UniProtKB:F1Q865 558
UniProtKB:Q803D4 558
UniProtKB:A0A2R8QCQ7 545
UniProtKB:A9JSX2 558
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations