Gene
acad8
- ID
- ZDB-GENE-040426-828
- Name
- acyl-CoA dehydrogenase family, member 8
- Symbol
- acad8 Nomenclature History
- Previous Names
-
- zgc:55874
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have acyl-CoA dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in lipid metabolic process and oxidation-reduction process. Orthologous to human ACAD8 (acyl-CoA dehydrogenase family member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55874 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Isobutyryl-CoA dehydrogenase deficiency | 611283 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR006089 | Acyl-CoA dehydrogenase, conserved site |
| Domain | IPR006091 | Acyl-CoA oxidase/dehydrogenase, middle domain |
| Domain | IPR009075 | Acyl-CoA dehydrogenase/oxidase, C-terminal |
| Domain | IPR013786 | Acyl-CoA dehydrogenase/oxidase, N-terminal |
| Family | IPR034178 | Isobutyryl-CoA dehydrogenase |
| Family | IPR052547 | Mitochondrial Isobutyryl-CoA Dehydrogenase |
| Homologous_superfamily | IPR009100 | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily |
| Homologous_superfamily | IPR036250 | Acyl-CoA dehydrogenase-like, C-terminal |
| Homologous_superfamily | IPR037069 | Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily |
| Homologous_superfamily | IPR046373 | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily |
Domain Details Per Protein
| Protein | Length | Acyl-CoA dehydrogenase, conserved site | Acyl-CoA dehydrogenase-like, C-terminal | Acyl-CoA dehydrogenase/oxidase, C-terminal | Acyl-CoA dehydrogenase/oxidase, N-terminal | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily | Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily | Acyl-CoA oxidase/dehydrogenase, middle domain | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily | Isobutyryl-CoA dehydrogenase | Mitochondrial Isobutyryl-CoA Dehydrogenase |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZYY0
|
418 |
Interactions and Pathways
No data available
Plasmids
No data available