ZFIN ID: ZDB-GENE-040426-793
Gene Name: RAS-like, family 11, member B
Gene Symbol: rasl11b    Nomenclature History

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Previous Names: fc21f04, wu:fc21f04, zgc:55750, zgc:77749

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have GTP binding activity and GTPase activity. Involved in mesendoderm development. Predicted to localize to the membrane. Is expressed in several structures, including axis; central nervous system; presumptive ectoderm; shield; and tail bud. Orthologous to human RASL11B (RAS like family 11 member B).
Genome Resources: Alliance (1),  Gene:393109 (1),  Ensembl(GRCz11):ENSDARG00000015611 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13617 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23686 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rasl11b N/A 1
    MO2-rasl11b N/A 1
    PHENOTYPE
    Data: Fig. 4 from P├ęzeron et al., 2008
    Observed in:
    DISEASE ASSOCIATED WITH rasl11b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rasl11b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mesendoderm development (more)
    Cellular Component membrane (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001806 Small GTPase
    Domain IPR005225 Small GTP-binding protein domain
    Family IPR020849 Small GTPase superfamily, Ras-type
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rasl11b-201 (1)    Ensembl 1713
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rasl11b No data available
    MARKER RELATIONSHIPS
    rasl11b Contained in: [BAC] CH73-249K16 (1)
    rasl11b Encodes: [EST] cegs2572 (1) (order this), fc21f04
    [cDNA] MGC:55750 (1), MGC:77749 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200140 (1)
    Genomic GenBank:CU693368 (1) 90103 bp
    Select Tool
    Polypeptide UniProtKB:Q6P0U3 (1) 244 aa
    Sequence Information (all 18)
    ORTHOLOGY for rasl11b ( Chr: 20 )
    CITATIONS (26)