Gene

exosc10

ID

ZDB-GENE-040426-781

Name

exosome component 10

Symbol

exosc10 Nomenclature History

Previous Names

zgc:55695 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have 3'-5'-exoribonuclease activity and single-stranded RNA binding activity. Predicted to be involved in RNA catabolic process and ncRNA 3'-end processing. Predicted to localize to nuclear exosome (RNase complex) and nucleolus. Orthologous to human EXOSC10 (exosome component 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7145587 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exosc10 Human Ortholog

No data available

Associated With exosc10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002121	HRDC domain
Domain	IPR002562	3'-5' exonuclease domain
Domain	IPR012588	Exosome-associated factor Rrp6, N-terminal
Domain	IPR049559	Rrp6-like, 3'-5' exonuclease domain
Family	IPR045092	Exosome complex exonuclease Rrp6-like
Homologous_superfamily	IPR010997	HRDC-like superfamily
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily
Homologous_superfamily	IPR044876	HRDC domain superfamily