Gene

rnf13

ID

ZDB-GENE-040426-772

Name

ring finger protein 13

Symbol

rnf13 Nomenclature History

Previous Names

wu:fj82g10
zgc:55660 (1)
zgc:77194

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in endomembrane system; intracellular membrane-bounded organelle; and membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 73. Orthologous to human RNF13 (ring finger protein 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55660 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rnf13 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 73	Alliance	Developmental and epileptic encephalopathy 73	618379

Associated With rnf13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR003137	PA domain
Domain	IPR044744	ZNRF4 /RNF13/RNF167, PA domain
Family	IPR051653	E3 ubiquitin-protein ligase and sorting receptor
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR046450	PA domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	E3 ubiquitin-protein ligase and sorting receptor	PA domain	PA domain superfamily	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	ZNRF4 /RNF13/RNF167, PA domain
UniProtKB:Q803J9	InterPro	377
UniProtKB:A0AB32TEQ5	InterPro	377

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rnf13-201 (1) Ensembl	Ensembl	4,631 nt	Select Tool ZFIN BLAST
mRNA	rnf13-202 (1) Ensembl	Ensembl	1,968 nt	Select Tool ZFIN BLAST
ncRNA	rnf13-002 (1) Ensembl	Ensembl	671 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations