Gene

sulf2a

ID
ZDB-GENE-040426-759
Name
sulfatase 2a
Symbol
sulf2a Nomenclature History
Previous Names
  • sulf2
  • zgc:55612 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to be involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; hypochord; neural plate; and neural tube. Orthologous to human SULF2 (sulfatase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sulf2a Human Ortholog
No data available
Associated With sulf2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR024607 Sulfatase, conserved site
Domain IPR000917 Sulfatase, N-terminal
Domain IPR024609 Extracellular sulfatase, C-terminal
Family IPR014615 Extracellular sulfatase
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily Extracellular sulfatase Extracellular sulfatase, C-terminal Sulfatase, conserved site Sulfatase, N-terminal
UniProtKB:A0A8M9QHJ3 765
UniProtKB:Q7ZVU8 873
UniProtKB:A0A8M2BGI3 874
UniProtKB:A0A8M9QLI6 873
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sulf2a-201 (1) Ensembl 3,651 nt
mRNA sulf2a-202 (1) Ensembl 774 nt
mRNA sulf2a-203 (1) Ensembl 405 nt
mRNA sulf2a-205 (1) Ensembl 2,628 nt
ncRNA sulf2a-002 (1) Ensembl 582 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations