Gene
lin28ab
- ID
- ZDB-GENE-040426-747
- Name
- lin-28 homolog Ab
- Symbol
- lin28ab Nomenclature History
- Previous Names
-
- lin28
- lin28a
- sb:cb650
- zgc:55584 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and polysome binding activity. Involved in chordate embryonic development; negative regulation of gene expression; and regeneration. Predicted to localize to cytoplasmic ribonucleoprotein granule; nucleus; and polysome. Is expressed in several structures, including Kupffer's vesicle; central nervous system; digestive system; neural plate; and neural tube. Orthologous to human LIN28A (lin-28 homolog A).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 30 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb650 (33 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001878 | Zinc finger, CCHC-type |
Domain | IPR002059 | Cold-shock protein Csp, DNA-binding |
Domain | IPR011129 | Cold-shock domain |
Family | IPR051373 | Lin-28 homolog RNA-binding protein |
Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
Homologous_superfamily | IPR036875 | Zinc finger, CCHC-type superfamily |
Domain Details Per Protein
Protein | Length | Cold-shock domain | Cold-shock protein Csp, DNA-binding | Lin-28 homolog RNA-binding protein | Nucleic acid-binding, OB-fold | Zinc finger, CCHC-type | Zinc finger, CCHC-type superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q803L0
|
202 | ||||||
UniProtKB:A0A2R8Q8W5
|
207 | ||||||
UniProtKB:I3IS11
|
194 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
lin28a-001
(1)
|
Ensembl | 2,020 nt | ||
mRNA |
lin28a-203
(1)
|
Ensembl | 607 nt | ||
mRNA |
lin28a-204
(1)
|
Ensembl | 547 nt | ||
mRNA |
lin28a-206
(1)
|
Ensembl | 908 nt | ||
mRNA |
lin28a-207
(1)
|
Ensembl | 6,269 nt | ||
mRNA |
lin28a-208
(1)
|
Ensembl | 5,479 nt | ||
mRNA |
lin28ab-202
(1)
|
Ensembl | 494 nt | ||
ncRNA |
lin28a-005
(1)
|
Ensembl | 793 nt |
Interactions and Pathways
No data available
Plasmids