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ZIRC
ZFIN ID: ZDB-GENE-040426-738
Gene Name: interleukin-1 receptor-associated kinase 4
Gene Symbol: irak4
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:55553

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of transcription, DNA-templated and response to  ...
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7161258]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014795Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32505 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH irak4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Invasive pneumococcal disease, recurrent isolated, 1 610799
    IRAK4 deficiency 607676
    DISEASE ASSOCIATED WITH irak4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 21)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM irak4 No data available
    MARKER RELATIONSHIPS
    irak4Encodes: [EST] IMAGE:7161258 (1) (order this)
    [cDNA] MGC:55553 (1) (order this), MGC:191952 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200163 (1)
    Genomic GenBank:CABZ01095583 (1) 12671bp
    Polypeptide UniProtKB:Q6IWL3 (1) 483aa
    Sequence Clusters UniGene:81680 (1)
    Sequence Information (all 22)
    OTHER irak4 GENE PAGES
  • Alliance (1)
  • Gene:393132 (1)
  • Ensembl(GRCz11):ENSDARG00000100534 (1)
  • ORTHOLOGY for irak4 (Chr: 25)
    CITATIONS (30)