Gene

brpf1

ID
ZDB-GENE-040426-731
Name
bromodomain and PHD finger containing, 1
Symbol
brpf1 Nomenclature History
Previous Names
  • zgc:55530 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits histone binding activity. Involved in anterior/posterior pattern specification. Localizes to chromatin. Is expressed in brain; digestive system; epithelium; head; and olfactory pit. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Laue et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brpf1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with dysmorphic facies and ptosis 617333
Associated With brpf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Domain IPR000313 PWWP domain
Domain IPR001487 Bromodomain
Domain IPR001965 Zinc finger, PHD-type
Domain IPR013087 Zinc finger C2H2-type
Domain IPR019542 Enhancer of polycomb-like, N-terminal
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR034732 Extended PHD (ePHD) domain
Domain IPR035502 BR140-related, PWWD domain
Domain IPR042008 BRPF1, PHD domain
Domain IPR042061 Peregrin, ePHD domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Domain Details Per Protein
Protein Length BR140-related, PWWD domain Bromodomain Bromodomain, conserved site Bromodomain-like superfamily BRPF1, PHD domain Enhancer of polycomb-like, N-terminal Extended PHD (ePHD) domain Peregrin, ePHD domain PWWP domain Zinc finger C2H2-type Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A0G2L9X9 1259
UniProtKB:H9GXF8 1248
UniProtKB:Q803M2 899
UniProtKB:B2YCZ4 1258
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations