waslb

ID

ZDB-GENE-040426-718

Name

WASP like actin nucleation promoting factor b

Symbol

waslb Nomenclature History

Previous Names

N-waspb (1)
wasl
reph (1)
rephaim (1)
unm_dmh22
unm_mh22
zgc:55478
zgc:77237

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable actin binding activity. Acts upstream of or within dermal bone morphogenesis; myeloid cell differentiation; and myoblast fusion. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including EVL; notochord; pectoral fin bud; periderm; and retina. Orthologous to human WASL (WASP like actin nucleation promoting factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55478 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With waslb Human Ortholog

No data available

Associated With waslb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000095	CRIB domain
Domain	IPR000697	WH1/EVH1 domain
Domain	IPR003124	WH2 domain
Domain	IPR033927	WASP family, EVH1 domain
Homologous_superfamily	IPR011026	Actin nucleation-promoting factor WAS, C-terminal
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036936	CRIB domain superfamily