Gene
ppp2r3c
- ID
- ZDB-GENE-040426-715
- Name
- protein phosphatase 2, regulatory subunit B'', gamma
- Symbol
- ppp2r3c Nomenclature History
- Previous Names
-
- zgc:55473
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in several processes, including cortical cytoskeleton organization; lymphocyte homeostasis; and positive regulation of B cell differentiation. Predicted to localize to centrosome and spindle. Human ortholog(s) of this gene implicated in male infertility. Orthologous to human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55473 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 36 | Alliance | Spermatogenic failure 36 | 618420 |
| Myoectodermal gonadal dysgenesis syndrome | 618419 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain pair | PP2A regulatory subunit B'', EF-hand domain | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma |
|---|---|---|---|---|---|
|
UniProtKB:B2GT25
|
457 | ||||
|
UniProtKB:Q803V3
|
457 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ppp2r3c-201
(1)
|
Havana | 1684 nt | |
| ncRNA |
ppp2r3c-002
(1)
|
Havana | 970 nt |
Interactions and Pathways
No data available
Plasmids
No data available