Gene
ppp2r3c
- ID
- ZDB-GENE-040426-715
- Name
- protein phosphatase 2, regulatory subunit B'', gamma
- Symbol
- ppp2r3c Nomenclature History
- Previous Names
-
- zgc:55473
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in cytoskeleton organization; lymphocyte homeostasis; and positive regulation of B cell differentiation. Predicted to act upstream of or within regulation of dephosphorylation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Orthologous to human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55473 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 36 | Alliance | Spermatogenic failure 36 | 618420 |
| Myoectodermal gonadal dysgenesis syndrome | 618419 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain pair | PP2A regulatory subunit B'', EF-hand domain | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma |
|---|---|---|---|---|---|
|
UniProtKB:B2GT25
|
457 | ||||
|
UniProtKB:Q803V3
|
457 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp2r3c-201
(1)
|
Ensembl | 1,684 nt | ||
| ncRNA |
ppp2r3c-002
(1)
|
Ensembl | 970 nt |
Interactions and Pathways
No data available
Plasmids
No data available