Gene

xab2

ID

ZDB-GENE-040426-685

Name

XPA binding protein 2

Symbol

xab2 Nomenclature History

Previous Names

zgc:63498
zgc:63949 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to be involved in generation of catalytic spliceosome for first transesterification step. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Orthologous to human XAB2 (XPA binding protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63498 (1 image)
MGC:63949 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With xab2 Human Ortholog

No data available

Associated With xab2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR055430	Pre-mRNA-splicing factor Syf1/CRNKL1-like, C-terminal HAT-repeats domain
Domain	IPR055433	Pre-mRNA-splicing factor Syf1-like, N-terminal HAT-repeats domain
Domain	IPR056350	Pre-mRNA-splicing factor SYF1, central HAT repeats domain
Family	IPR045075	Pre-mRNA-splicing factor Syf1-like
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR003107	HAT (Half-A-TPR) repeat
Repeat	IPR019734	Tetratricopeptide repeat