ZFIN is now using GRCz12tu for Genomic Data
Gene
crkl
- ID
- ZDB-GENE-040426-2951
- Name
- v-crk avian sarcoma virus CT10 oncogene homolog-like
- Symbol
- crkl Nomenclature History
- Previous Names
-
- wu:fa55g05
- wu:fj60e01
- zgc:63469 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. Acts upstream of or within myoblast fusion; pronephros morphogenesis; and retina layer formation. Predicted to be active in cytoplasm. Is expressed in nervous system; otic vesicle; and pronephros. Human ortholog(s) of this gene implicated in chronic myeloid leukemia. Orthologous to human CRKL (CRK like proto-oncogene, adaptor protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63469 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CRK, N-terminal SH3 domain | SH2 domain | SH2 domain superfamily | SH3 domain | SH3-like domain superfamily | Tyrosine-phosphorylated adapter molecule |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6PH06 | InterPro | 305 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers