Gene

creb3l3l

ID
ZDB-GENE-040426-2942
Name
cAMP responsive element binding protein 3-like 3 like
Symbol
creb3l3l Nomenclature History
Previous Names
  • creb3l3 (1)
  • wu:fj05f07
  • zgc:66452
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and cAMP response element binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and positive regulation of transcription by RNA polymerase II. Predicted to localize to several cellular components, including endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in central nervous system; liver; notochord; sensory system; and yolk syncytial layer. Orthologous to human CREB3 (cAMP responsive element binding protein 3).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With creb3l3l Human Ortholog
No data available
Associated With creb3l3l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Family IPR001630 cAMP response element binding (CREB) protein
Family IPR029806 cAMP-responsive element-binding protein 3-like protein 3
Domain Details Per Protein
Protein Length Basic-leucine zipper domain cAMP response element binding (CREB) protein cAMP-responsive element-binding protein 3-like protein 3
UniProtKB:F6NIK9 503
UniProtKB:A0A0R4IAM1 219
UniProtKB:Q7SXC2 392
UniProtKB:A0A0R4IB23 381
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Orthology Note
Woods, et al. (2005. Genome Res. 15:1307-1914.) stated orthology to CREB3L3 supported by amino acid sequence identity. Subsequent data supported that a different gene (ZDB-GENE-030131-4298) is the ortholog of human CREB3L3 based on higher amino acid sequence identity as well as conserved location.
Citations