Gene

nup133

ID
ZDB-GENE-040426-2941
Name
nucleoporin 133
Symbol
nup133 Nomenclature History
Previous Names
  • wu:fa04e09
  • zgc:55311
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to be a structural constituent of nuclear pore. Predicted to be involved in poly(A)+ mRNA export from nucleus; protein import into nucleus; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in kinetochore and nucleus. Predicted to be part of nuclear pore outer ring. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Used to study Galloway-Mowat syndrome 1. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome and nephrotic syndrome type 18. Orthologous to human NUP133 (nucleoporin 133).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nup133 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nephrotic syndrome type 18 Alliance Nephrotic syndrome, type 18 618177
?Galloway-Mowat syndrome 8 618349
Associated With nup133 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007187 Nucleoporin, Nup133/Nup155-like, C-terminal
Domain IPR014908 Nucleoporin, Nup133/Nup155-like, N-terminal
Family IPR037624 Nuclear pore complex protein Nup133-like
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Domain Details Per Protein
Protein Length Nuclear pore complex protein Nup133-like Nucleoporin, Nup133/Nup155-like, C-terminal Nucleoporin, Nup133/Nup155-like, N-terminal WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:F1QNV4 1136
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations