Gene
tfdp1a
- ID
- ZDB-GENE-040426-2883
- Name
- transcription factor Dp-1, a
- Symbol
- tfdp1a Nomenclature History
- Previous Names
-
- tfdp1l (1)
- wu:fb94b07
- wu:fc52a06
- zgc:55487
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of cell cycle. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in mismatch repair cancer syndrome. Orthologous to several human genes including TFDP1 (transcription factor Dp-1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55487 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Domain | IPR014889 | Transcription factor DP, C-terminal |
Family | IPR015648 | Transcription factor DP |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
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Domain Details Per Protein
Protein | Additional Resources | Length | E2F/DP family, winged-helix DNA-binding domain | E2F-DP heterodimerization region | Transcription factor DP | Transcription factor DP, C-terminal | Transcription factor DP, C-terminal domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q803N1 | InterPro | 409 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
tfdp1a-201
(1)
|
Ensembl | 2,317 nt | ||
mRNA |
tfdp1a-202
(1)
|
Ensembl | 749 nt | ||
mRNA |
tfdp1a-204
(1)
|
Ensembl | 875 nt | ||
ncRNA |
tfdp1a-004
(1)
|
Ensembl | 668 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-160B11 | ZFIN Curated Data | |
Encodes | EST | fb94b07 | ||
Encodes | EST | fc52a06 | ||
Encodes | cDNA | MGC:55487 | ZFIN Curated Data | |
Encodes | cDNA | MGC:192879 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_213492 (1) | 2537 nt | ||
Genomic | GenBank:BX294188 (1) | 261943 nt | ||
Polypeptide | UniProtKB:Q803N1 (1) | 409 aa |
- Cai, X., Huang, Y., Chen, H., Qi, Q., Xu, M., Xu, P., Wu, X. (2021) Identification and functional characterization of the transcription factor coding Dp1 gene in large yellow croaker Pseudosciaena crocea. Heliyon. 7:e06299
- Zhou, F., Rayamajhi, D., Ravi, V., Narasimhan, V., Chong, Y.L., Lu, H., Venkatesh, B., Roy, S. (2020) Conservation as well as divergence in Mcidas function underlies the differentiation of multiciliated cells in vertebrates. Developmental Biology. 465(2):168-177
- Chong, Y.L., Zhang, Y., Zhou, F., Roy, S. (2018) Distinct requirements of E2f4 versus E2f5 activity for multiciliated cell development in the zebrafish embryo. Developmental Biology. 443(2):165-172
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Castro, L.F., Gonçalves, O., Mazan, S., Tay, B.H., Venkatesh, B., Wilson, J.M. (2013) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history. Proceedings. Biological sciences. 281:20132669
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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