Gene
xrn2
- ID
- ZDB-GENE-040426-2874
- Name
- 5'-3' exoribonuclease 2
- Symbol
- xrn2 Nomenclature History
- Previous Names
-
- wu:fb38g12
- wu:fj53d06
- zgc:55717
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable 5'-3' exoribonuclease activity and RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process. Predicted to act upstream of or within nucleobase-containing compound metabolic process. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma and lung cancer. Orthologous to human XRN2 (5'-3' exoribonuclease 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55717 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | 5'-3' exoribonuclease | 5'-3' exoribonuclease type 2 | Xrn1, helical domain | Xrn1, N-terminal |
---|---|---|---|---|---|
UniProtKB:A0A0R4ISJ3
|
952 | ||||
UniProtKB:A0A8M2B7S3
|
938 |
Interactions and Pathways
No data available
Plasmids
No data available