faf1

ID

ZDB-GENE-040426-2863

Name

Fas (TNFRSF6) associated factor 1

Symbol

faf1 Nomenclature History

Previous Names

fc25h12
wu:fc25h12 (1)
zgc:55752 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable NF-kappaB binding activity and ubiquitin binding activity. Acts upstream of or within cartilage development; fin regeneration; and pharyngeal system development. Predicted to be active in endoplasmic reticulum and nucleus. Is expressed in pharyngeal arch; pharyngeal arch 1; pharyngeal arch 2; and pharyngeal arch 3-7. Orthologous to human FAF1 (Fas associated factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7149405 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Ghassibe-Sabbagh et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With faf1 Human Ortholog

No data available

Associated With faf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000626	Ubiquitin-like domain
Domain	IPR001012	UBX domain
Domain	IPR006577	UAS
Domain	IPR033043	FAS-associated factor 1-like, UBX domain
Domain	IPR044541	FAF1, UBA-like domain
Domain	IPR049483	Fas-associated factor 1/2-like, UAS domain
Family	IPR050730	UBX domain-containing protein
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily