Gene
fpgs
- ID
- ZDB-GENE-040426-2781
- Name
- folylpolyglutamate synthase
- Symbol
- fpgs Nomenclature History
- Previous Names
-
- fk51d09
- wu:fk49h03
- wu:fk51d09
- zgc:63807
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in tetrahydrofolylpolyglutamate biosynthetic process. Predicted to act upstream of or within folic acid-containing compound biosynthetic process and one-carbon metabolic process. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; liver; nervous system; optic vesicle; and yolk syncytial layer. Orthologous to human FPGS (folylpolyglutamate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63807 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018109 | Folylpolyglutamate synthetase, conserved site |
| Family | IPR001645 | Folylpolyglutamate synthetase |
| Family | IPR023600 | Folylpolyglutamate synthase, eukaryota |
| Homologous_superfamily | IPR036565 | Mur-like, catalytic domain superfamily |
| Homologous_superfamily | IPR036615 | Mur ligase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Folylpolyglutamate synthase, eukaryota | Folylpolyglutamate synthetase | Folylpolyglutamate synthetase, conserved site | Mur ligase, C-terminal domain superfamily | Mur-like, catalytic domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:F1Q7N0
|
572 |
Interactions and Pathways
No data available
Plasmids
No data available