Gene
spg21
- ID
- ZDB-GENE-040426-2722
- Name
- SPG21 abhydrolase domain containing, maspardin
- Symbol
- spg21 Nomenclature History
- Previous Names
-
- wu:fd07h02
- zgc:73091 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable CD4 receptor binding activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in cytosol and trans-Golgi network transport vesicle. Human ortholog(s) of this gene implicated in Mast syndrome and hereditary spastic paraplegia. Orthologous to human SPG21 (SPG21 abhydrolase domain containing, maspardin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73091 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mast syndrome | Alliance | Mast syndrome | 248900 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Alpha/beta hydrolase fold-1 | Maspardin |
|---|---|---|---|---|---|
| UniProtKB:Q6PC62 | InterPro | 311 |
Interactions and Pathways
No data available
Plasmids
No data available