ZFIN ID: ZDB-GENE-040426-2700
Gene Name: protein phosphatase 2, regulatory subunit A, beta a
Gene Symbol: ppp2r1ba    Nomenclature History

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Previous Names: ppp2r1a, wu:fa02h04, zgc:56296

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to contribute to protein serine/threonine phosphatase activity. Predicted to localize to cytoplasm and protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 36. Orthologous to several human genes including PPP2R1B (protein phosphatase 2 scaffold subunit Abeta).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000007791 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56296]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6912486]
  6 figures (0 images) from Rauch et al., 2003 [fb18a06]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029131Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7008 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ppp2r1ba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    lung cancer Alliance Lung cancer, somatic 211980
    DISEASE ASSOCIATED WITH ppp2r1ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytoplasm (more)
    Molecular Function protein phosphatase regulator activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp2r1ba-201 (1)    Ensembl 2883
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp2r1ba No data available
    MARKER RELATIONSHIPS
    ppp2r1ba Contained in: [BAC] DKEY-71L1 (1) (order this)
    ppp2r1ba Encodes: [EST] fa02h04 (1), fb18a06 (1) (order this), IMAGE:6912486 (1)
    [cDNA] MGC:56296 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA GenBank:BC046055 (1) 2581 nt
    Genomic GenBank:BX901896 (1) 100093 nt
    Select Tool
    Polypeptide UniProtKB:A5PMV7 (1) 589 aa
    Sequence Information (all 8)
    ORTHOLOGY for ppp2r1ba ( Chr: 5 )
    CITATIONS (20)