Gene
ehhadh
- ID
- ZDB-GENE-040426-2581
- Name
- enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
- Symbol
- ehhadh Nomenclature History
- Previous Names
-
- l-pbe (1)
- zgc:77526
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in Fanconi syndrome. Is expressed in male organism. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77526 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi renotubular syndrome 3 | Alliance | ?Fanconi renotubular syndrome 3 | 615605 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR006180 | 3-hydroxyacyl-CoA dehydrogenase, conserved site |
| Conserved_site | IPR018376 | Enoyl-CoA hydratase/isomerase, conserved site |
| Domain | IPR006108 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal |
| Domain | IPR006176 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding |
| Family | IPR001753 | Enoyl-CoA hydratase/isomerase |
| Homologous_superfamily | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR029045 | ClpP/crotonase-like domain superfamily |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | 3-hydroxyacyl-CoA dehydrogenase, conserved site | 3-hydroxyacyl-CoA dehydrogenase, C-terminal | 3-hydroxyacyl-CoA dehydrogenase, NAD binding | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | ClpP/crotonase-like domain superfamily | Enoyl-CoA hydratase/isomerase | Enoyl-CoA hydratase/isomerase, conserved site | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYL3
|
718 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ehhadh-201
(1)
|
Ensembl | 2,480 nt |
Interactions and Pathways
No data available
Plasmids
No data available