Gene
irf2bp2b
- ID
- ZDB-GENE-040426-2574
- Name
- interferon regulatory factor 2 binding protein 2b
- Symbol
- irf2bp2b Nomenclature History
- Previous Names
-
- irf2bp2
- wu:fa12b04
- wu:fb73g01
- zgc:63864
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have transcription corepressor activity and ubiquitin protein ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Is expressed in several structures, including immature eye; musculature system; nervous system; notochord; and pronephric duct. Orthologous to human IRF2BP2 (interferon regulatory factor 2 binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63864 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Wang et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| common variable immunodeficiency 14 | Alliance | ?Immunodeficiency, common variable, 14 | 617765 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily | Interferon regulatory factor 2-binding protein 1 & 2, zinc finger |
|---|---|---|---|
|
UniProtKB:Q7T2G1
|
501 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
irf2bp2b-201
(1)
|
Ensembl | 2,117 nt |
Interactions and Pathways
No data available
Plasmids
No data available