Gene
egln3
- ID
- ZDB-GENE-040426-2541
- Name
- egl-9 family hypoxia-inducible factor 3
- Symbol
- egln3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have L-ascorbic acid binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is expressed in axial mesoderm; liver; margin; and neural plate. Orthologous to human EGLN3 (egl-9 family hypoxia inducible factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907425 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hypoxia-inducible factor prolyl hydroxylases | Oxoglutarate/iron-dependent dioxygenase domain | Prolyl 4-hydroxylase, alpha subunit | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6NY85
|
236 | ||||
|
UniProtKB:A0A8M2BH64
|
271 |
Interactions and Pathways
No data available
Plasmids
No data available